Introduction: Hyperuricemia is defined as a level of serum uric acid greater\nthan or equal to 70 mg/l (420 �¼mol/l) in men and 60 mg/l (360 �¼mol/l) in\nwomen. Several studies have shown that it is a risk factor or a factor of progression\nof chronic kidney disease. Recent experimental and epidemiological\ndata correlate the association of hyperuricemia with chronic kidney disease\n(CKD), arterial hypertension and cardiovascular diseases, thus raising the\nquestion of the usefulness of therapeutics in the prevention of renal diseases.\nThe objective of this study is to seek a link between chronic kidney disease\nand hyperuricemia. Materials and Methods: This is a descriptive and analytical\nstudy conducted at hemodialysis unit and cardiology service of General\nHospital of National reference of Nâ��Djamena (Chad) from 1th January to 1th\nOctober 2013 (10 months). We included all chronic kidney disease patients\nhospitalized in hemodialysis unit and cardiology service who presented associated\nhyperuricemia. Results: There were 712 CKD patients who were hospitalized.\nAmong them, there were 108 patients who were included in the\nstudy and who had hyperuricemia as a prevalence of 15.20%. The average age\nof patients was 35.5 years and the sex ratio was 3/1. The age group between 40\nto 60 years represented 54.6%. There were 41.7% of traders. Hypertensive patients\naccounted for 49.1%; association of diabetes and hypertension was\nnoted in 12.90%. Renal insufficiency was moderate in 43.5% of patients.\nHyperuricemia was present in more than 90% of patients. Profession, age,\nhematuria, proteinuria and hypertension were statistically positively related to\nhyperuricemia. Treatment consisted of prescribing allopurinol in 84% of patients.\nIn more than 11% of patients the progression was unfavorable. Conclusion:\nThe implication of hyperuricemia in chronic kidney disease has been\nproved in several recent studies. However, randomized studies at very long\nscales have to be carried out to conclude from its real impact on the prevention\nand treatment of chronic kidney disease.
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